Many questions are associated with the chemical compound Isotretinoin commonly referred to by its original brand name Accutane by the pharmaceutical giant Hoffmann La Roche. Accutane is also known under the brand name Roaccutane in the United Kingdom.
Since the discontinuation of Accutane by Roche in 2009 many generic preparations of the drug have been introduced on to the market.
In today’s article I want to cover some specific questions surrounding the action, efficacy and safety of the Accutane.
How does Accutane Work To Reduce Acne?
Although doctors and specialist dermatologists put forward a wide range of opinions as to the how this chemical is able to permanently cure acne, no one knows for sure its exact mechanism of action.
The most plausible explanation was put forward by a UK dermatologist who states that the chemical when ingested orally gradually builds up in the blood and actually reduces the size of the sebaceous glands. He does not suggest that the actual number of these oil producing sebaceous glands are reduced but their actual size.
When I asked him how this was possible? Without getting overly technical he explained that the protein structure of the sebaceous gland is permanently changed causing it to shrink in size hence reducing the over output of sebum onto the skin surface.
Is Accutane Effective In The Treatment Of Acne?
Accutane has been used to effectively treat over 13 million patients worldwide for over 25 years. The results attained after a 6 month course of Accutane are unrivalled by any other drug currently on the market today. It is believed that the reason why Accutane is so successful in treating acne is found in its ability to target the root cause of the problem.
It is simple to understand that if you can permanently reduce the output of sebum onto the skin surface than the pores are far less likely to clog up and therefore no amount of surface bacteria can enter the blocked pore and cause acne.
It is for this reason that the use of topical anti bacterial creams or the use of oral anti biotics in the treatment of acne is completely futile as neither target the root cause of acne.
Is Accutane Safe In The Treatment Of Acne?
All medication however mild will produce some for m of side effect. Accutane likewise has some potentially serious side effects which need to be managed under the supervision of a doctor. For the vast majority of patients taking Accutane the side effects amount to nothing more than an annoyance. This can manifest itself in the form of dry skin, chapped lips, itching, minor spells of dizziness and the list goes on.
Accutane should never be taken if you are pregnant or plan to get pregnant whilst on Accutane as it has been linked with serious birth defects.
In summary
Accutane is a powerful and effective medicine in the treatment of acne and if used correctly will leave you acne free for life.
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